Longevue — 12 Hallmarks of Aging

Longevue is a free interactive guide to the 12 Hallmarks of Aging (López-Otín et al., Cell 2023). Explore each biological driver of aging, evidence-backed habit deep dives, and practical mitigation tactics for healthy longevity.

About Longevue

Longevue maps the twelve hallmarks of aging from López-Otín et al., Cell (2023) into an interactive diagram with evidence-backed habit deep dives on UV protection, body fat distribution, and practical mitigation tactics.

Deep dive topics

UV protection — UV protection blocks UVA, UVB, and high-energy visible light that drive DNA damage, photoaging, and skin cancer—daily broad-spectrum SPF 30+ is the baseline defense.
Body fat — Body fat distribution—especially visceral (abdominal) versus subcutaneous depots—drives chronic inflammation and metabolic risk as much as total weight.
Amino acids — The 20 proteinogenic amino acids—each with distinct roles in protein synthesis, signaling, and metabolic pathways tied to repair and longevity.
Nucleotide bases — The five canonical nucleobases—adenine, cytosine, guanine, thymine, and uracil—that pair in DNA and RNA and anchor replication, repair, and epigenetic chemistry.